A 30mV input battery-less power management system

This paper presents a fully-integrated on chip battery-less power management system through energy harvesting circuit developed in a 130nm CMOS process. A 30mV input voltage from a TEG is able to be boosted by the proposed Complementary Metal-Oxide-Semiconductor (CMOS) voltage booster and a dynamic closed loop power management to a regulated 1.2V. Waste body heat is harvested through Thermoelectric energy harvesting to power up low power devices such as Wireless Body Area Network. A significant finding where 1 Degree Celsius thermal difference produces a minimum 30mV is able to be boosted to 1.2V. Discontinuous Conduction Mode (DCM) digital control oscillator is the key component for the gate control of the proposed voltage booster. Radio Frequency (RF) rectifier is utilized to act as a start-up mechanism for voltage booster and power up the low voltage closed loop power management circuit. The digitally control oscillator and comparator are able to operate at low voltage 600mV which are powered up by a RF rectifier, and thus to kick-start the voltage booster

Design of a high efficiency multiple-inputs single-output switch capacitor-based DC-DC converter for energy harvesting system

Thermoelectric generators (TEGs) module acts as a source to harvest thermal energy and convert the temperature gradient into DC voltage. Due to its low electricity produced, the DC-DC converter is the key module to boost minimal voltage to feasible electricity. The setback of existing converter topology such as inductor-based is the off-chip component makes fully integrated on-chip system a challenging task. Thus, the research focuses on the design of a cross-coupled charge pump in power management energy harvesting circuitry together with a start-up circuit and control circuit to form a regulated battery-less power management system. Multiple energy sources, RF and thermal energy have been used as the supply for the auxiliary circuitry and cross-coupled charge pump in the research. The proposed cross-coupled charge pump is designed based on an analytical approach that investigates the transistor’s size, the switching pulse’s frequency, the switching pulse’s slew rate and the capacitor’s size. The peak efficiency of the cross-coupled charge pump has been improved by analyzing these four main parameters. The proposed system can function at a minimum voltage of 30mV and achieve a step-up voltage of 1.2V in a fully integrated chip. The major contribution of this work is the design of the cross-coupled charge pump has successfully achieved an efficiency of 70.86%. RF and TEG signal are utilized as voltage supply and input for the entire power management system. Due to the multiple energy harvesting sources, auxiliary circuitries can be fully integrated to form an on-chip power management system without an external inductor, capacitor and antenna to support the power management system and only occupy a chip size of 1.9358〖mm〗^2. Implementation of on–chip antenna for RF auxiliary circuitry achieves a more compressive fully integrated on-chip system. In overall, the entire design configuration has managed to reduce the mismatch of the off-chip component on the on-chip power management system as well as to reduce the package of the chip size

A 30mV Input Battery-Less Power Management System

This paper presents a fully-integrated on chip battery-less power management system through energy harvesting circuit developed in a 130nm CMOS process. A 30mV input voltage from a TEG is able to be boosted by the proposed Complementary Metal-Oxide-Semiconductor (CMOS) voltage booster and a dynamic closed loop power management to a regulated 1.2V. Waste body heat is harvested through Thermoelectric energy harvesting to power up low power devices such as Wireless Body Area Network. A significant finding where 1 Degree Celsius thermal difference produces a minimum 30mV is able to be boosted to 1.2V. Discontinuous Conduction Mode (DCM) digital control oscillator is the key component for the gate control of the proposed voltage booster. Radio Frequency (RF) rectifier is utilized to act as a start-up mechanism for voltage booster and power up the low voltage closed loop power management circuit. The digitally control oscillator and comparator are able to operate at low voltage 600mV which are powered up by a RF rectifier, and thus to kick-start the voltage booste

A Complete Design And Development Of A Miniature Battery-Less Power Management Unit For Powering Biomedical Implant

With the emerging of micro and nanotechnology in energy harvesting system, small size, self-powered, fully integrated on-chip battery-less power management system is preferable. However, a miniature power management system with an ultra-low input voltage as well as low kick- start voltage is the challenging task in the research. For this reason, a single inductor based dynamic closed loop battery-less power management systemis proposed by using only 30 mV or 1 °C from the thermoelectric generator to boost up to a minimum of 1.2V. Different topology of miniature boost converters in terms of input voltage, start-up voltage and form factor were reviewed. The focus highlighted on different configurations of CMOS switch inductor boost converter used within energy harvesting circuitry. The design has been developed in 130 nm Silterra CMOS process technology and only occupies an area of 1.0059

Genome Sequence of the Brown Norway Rat Yields Insights Into Mammalian Evolution

The laboratory rat (Rattus norvegicus) is an indispensable tool in experimental medicine and drug development, having made inestimable contributions to human health. We report here the genome sequence of the Brown Norway (BN) rat strain. The sequence represents a high-quality 'draft' covering over 90% of the genome. The BN rat sequence is the third complete mammalian genome to be deciphered, and three-way comparisons with the human and mouse genomes resolve details of mammalian evolution. This first comprehensive analysis includes genes and proteins and their relation to human disease, repeated sequences, comparative genome-wide studies of mammalian orthologous chromosomal regions and rearrangement breakpoints, reconstruction of ancestral karyotypes and the events leading to existing species, rates of variation, and lineage-specific and lineage-independent evolutionary events such as expansion of gene families, orthology relations and protein evolution

Open data from the first and second observing runs of Advanced LIGO and Advanced Virgo

Advanced LIGO and Advanced Virgo are monitoring the sky and collecting gravitational-wave strain data with sufficient sensitivity to detect signals routinely. In this paper we describe the data recorded by these instruments during their first and second observing runs. The main data products are gravitational-wave strain time series sampled at 16384 Hz. The datasets that include this strain measurement can be freely accessed through the Gravitational Wave Open Science Center at http://gw-openscience.org, together with data-quality information essential for the analysis of LIGO and Virgo data, documentation, tutorials, and supporting software

Search for intermediate-mass black hole binaries in the third observing run of Advanced LIGO and Advanced Virgo

International audienceIntermediate-mass black holes (IMBHs) span the approximate mass range 100−105 M⊙, between black holes (BHs) that formed by stellar collapse and the supermassive BHs at the centers of galaxies. Mergers of IMBH binaries are the most energetic gravitational-wave sources accessible by the terrestrial detector network. Searches of the first two observing runs of Advanced LIGO and Advanced Virgo did not yield any significant IMBH binary signals. In the third observing run (O3), the increased network sensitivity enabled the detection of GW190521, a signal consistent with a binary merger of mass ∼150 M⊙ providing direct evidence of IMBH formation. Here, we report on a dedicated search of O3 data for further IMBH binary mergers, combining both modeled (matched filter) and model-independent search methods. We find some marginal candidates, but none are sufficiently significant to indicate detection of further IMBH mergers. We quantify the sensitivity of the individual search methods and of the combined search using a suite of IMBH binary signals obtained via numerical relativity, including the effects of spins misaligned with the binary orbital axis, and present the resulting upper limits on astrophysical merger rates. Our most stringent limit is for equal mass and aligned spin BH binary of total mass 200 M⊙ and effective aligned spin 0.8 at 0.056 Gpc−3 yr−1 (90% confidence), a factor of 3.5 more constraining than previous LIGO-Virgo limits. We also update the estimated rate of mergers similar to GW190521 to 0.08 Gpc−3 yr−1.Key words: gravitational waves / stars: black holes / black hole physicsCorresponding author: W. Del Pozzo, e-mail: [email protected]† Deceased, August 2020

Prospective observational cohort study on grading the severity of postoperative complications in global surgery research

Background The Clavien–Dindo classification is perhaps the most widely used approach for reporting postoperative complications in clinical trials. This system classifies complication severity by the treatment provided. However, it is unclear whether the Clavien–Dindo system can be used internationally in studies across differing healthcare systems in high- (HICs) and low- and middle-income countries (LMICs). Methods This was a secondary analysis of the International Surgical Outcomes Study (ISOS), a prospective observational cohort study of elective surgery in adults. Data collection occurred over a 7-day period. Severity of complications was graded using Clavien–Dindo and the simpler ISOS grading (mild, moderate or severe, based on guided investigator judgement). Severity grading was compared using the intraclass correlation coefficient (ICC). Data are presented as frequencies and ICC values (with 95 per cent c.i.). The analysis was stratified by income status of the country, comparing HICs with LMICs. Results A total of 44 814 patients were recruited from 474 hospitals in 27 countries (19 HICs and 8 LMICs). Some 7508 patients (16·8 per cent) experienced at least one postoperative complication, equivalent to 11 664 complications in total. Using the ISOS classification, 5504 of 11 664 complications (47·2 per cent) were graded as mild, 4244 (36·4 per cent) as moderate and 1916 (16·4 per cent) as severe. Using Clavien–Dindo, 6781 of 11 664 complications (58·1 per cent) were graded as I or II, 1740 (14·9 per cent) as III, 2408 (20·6 per cent) as IV and 735 (6·3 per cent) as V. Agreement between classification systems was poor overall (ICC 0·41, 95 per cent c.i. 0·20 to 0·55), and in LMICs (ICC 0·23, 0·05 to 0·38) and HICs (ICC 0·46, 0·25 to 0·59). Conclusion Caution is recommended when using a treatment approach to grade complications in global surgery studies, as this may introduce bias unintentionally